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Organic compounds that contain an aromatic ring with one or more hydrogen atoms replaced by a halogen atom; also known as haloarene or halogenoarene. Halogen atoms include bromine, chlorine, fluorine, iodine.
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2-Amino-3-methylimidazo[4,5-f]quinoline is a heterocyclic aromatic compound used in research on mutagenicity and food-derived carcinogens. It is supplied for laboratory research use only and requires cautious handling due to reported genotoxicity.
Used in mutagenicity and toxicology studies.
Reported as a food-derived carcinogen relevant to cooked meats and tobacco smoke.
Provided as a small-mass solid suitable for analytical and reference use.
Identified by CAS 76180-96-6; formula C11H10N4; Mw 198.22 g·mol⁻¹.
Suitable for analytical standards and metabolic studies.
For research use only; not for human or clinical use.
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Nintedanib (BIBF 1120 CAS 656247-17-5) is an orally bioavailable small-molecule tri-kinase inhibitor that targets vascular endothelial growth factor receptors (VEGFR1-3) fibroblast growth factor receptors (FGFR1-3) and platelet-derived growth factor receptors (PDGFR / ) By inhibiting these receptor pathways at nanomolar concentrations (IC50 20 100 nmol/L) Nintedanib disrupts angiogenesis signaling and demonstrates antiangiogenic activity It is extensively investigated in preclinical and clinical research for idiopathic pulmonary fibrosis (IPF) as well as oncology including non-small-cell lung carcinoma ovarian cancer colorectal cancer and hepatocellular carcinoma
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5-Iodo-CTP is a nucleotide analog derived from cytidine triphosphate (CTP) Due to its triphosphate structure it serves as a substrate for RNA polymerases and becomes incorporated into nascent RNA strands during transcription Incorporation of the iodine atom into RNA molecules facilitates their subsequent detection and analysis Thus 5-Iodo-CTP finds utility in studying RNA structure-function relationships analyzing RNA synthesis and stability and characterizing RNA-protein interactions Additionally the iodine substituent integrated within RNA offers a convenient handle for cross-linking or probing RNA-associated molecular events
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